Intensive Anti-Wrinkle Transdermic Care for mature skin with deep wrinkles and furrows. sh-Polypeptide-1 and sh-Polypeptide-5 have a strong anti-wrinkle action with revitalizing and stimulating properties for skin cell proliferation; Caprooyl Tetrapeptide-3 is an anti-wrinkle active that stimulates the formation of laminine and fibronectine, components of the dermo-epidermal junction; Hydrolyzed RNA and DNA have a cellular repairing action; Magnesium Gluconate creates the best conditions for a relaxing effect on expression lines; Tocopheryl Acetate anti-oxidant action neutralizes the free radicals.