Calming Transdermic Care for Flushed, Irritated, Sensitized Skin. Panthenol with its marked humectant properties has a softening and protective effect on the skin; Niacinamide improves the barrier effect of the skin, strengthening it; Bisabolol derives from chamomile and has a soothing and calming effect that gives relief to sensitized skin; Glycyrrhetinic Acid has anti-reddening properties and is particularly suitable for flushed, reddened or blotched skins.