Anti-Wrinkle Transdermic Care for Lip Contour Lines. sh-Polypeptide-1 stimulates cells proliferation; Caprooyl Tetrapeptide-3 is an anti-wrinkle active that stimulates the formation of laminine and fibronectine (dermo-epidermal junction); Hydrolyzed RNA and DNA have a cellular repairing action; Sesamum Indicum Seed Extract has a plumping effect on lip contour wrinkles.